What is mast cell activation syndrome?
Mast cell activation syndrome (MCAS) is a disorder characterized by episodes of symptoms related to hyper-reactivity of mast cells. Symptoms vary but may include hot flushing, stomach pain or nausea, lightheadness, heart palpitations, and more. Treatment for MCAS is not well established.
How do members experience mast cell activation syndrome?
Top 5 symptoms reported by people with mast cell activation syndrome*
Common symptoms
How bad it is
What people are taking for it
Common symptom
Heightened sense of smell (hyperosmia)
How bad it is
What people are taking for it
Nothing reported yet
Common symptom
Fatigue
How bad it is
What people are taking for it
Common symptom
Pain
How bad it is
What people are taking for it
Common symptom
Gastrointestinal dysmotility
How bad it is
What people are taking for it
Nothing reported yet
*Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
Top treatments taken by people for mast cell activation syndrome*
Who has mast cell activation syndrome on PatientsLikeMe?
| Age | Proportion | # of patients |
|---|---|---|
| <20 | 6 | |
| 20s | 63 | |
| 30s | 80 | |
| 40s | 93 | |
| 50s | 82 | |
| 60s | 57 | |
| 70+ | 18 |
Distribution of sex
| Sex | Proportion | # of patients |
|---|---|---|
| Male | 43 | |
| Female | 356 |