
Estimated reading time: 3 minutes
Recent reports have come up regarding a phenomenon dubbed "Ozempic Personality." Apparently, there have been occasional mood changes associated with the use of GLP-1 medications, primarily Ozempic and Wegovy. These reports suggest changes in mood and demeanor among users, including increased anxiety, depression, and decreased interest in previously enjoyed activities. If you have seen anything about this in the news lately, don't worry! PatientsLikeMe is here to set the record straight.
GLP-1 Medications
GLP-1 medications were originally created to help treat type 2 diabetes. Drugs like Ozempic and Wegovy, however, were quickly shown to have other effects! They are now commonly prescribed for weight loss due to their ability to reduce appetite and increase feelings of fullness. These drugs have shown remarkable effectiveness in aiding weight loss, with some patients experiencing significant reductions in body weight.
GLP-1 medications primarily affect appetite regulation and satiety through interactions with gut hormones. While the exact mechanism behind potential mood changes is unclear, some speculate that alterations in dopamine signaling or changes in food-related behaviors could play a role.
New Terminology
Terms like "Ozempic face" and "Ozempic butt" have emerged online to describe the visible and physical effects of GLP-1 medications on weight loss. While not scientifically validated, these terms reflect the impact of these drugs on individuals' bodies.
Lately, the term "Ozempic personality" has gained attention. It suggests changes in mood and mental health among users. Anecdotal reports on social media and news outlets have highlighted symptoms such as worsened mood, increased anxiety and depression, and decreased libido. It is fairly common for people to wonder about the link between GLP-1 medications and mood changes. Not too long ago, the FDA came out with a report that dispelled the idea the use of Ozempic led to suicidal thoughts or actions. It does not.
What Do The Experts Say?
Scientific evidence linking GLP-1 medications to changes in mood is limited. Large-scale studies have found no direct association between these drugs and mental health issues. It should be noted that most drugs have both physical and mental side effects! Ozempic is no different. While we do not fully understand how it can effect the brain, a few things are clear. Weight loss itself can alter behavior and mood, as well as drain energy. It can also have tremendous positive effects, such as heightened self-confidence and self esteem.
Experts caution against attributing changes in mood solely to medication use. It is always important to consider the benefits and risks of GLP-1 medications in managing obesity and related conditions. Be sure to seek support from healthcare providers and address concerns together.

While reports of "Ozempic personality" have started to come out, the scientific basis for this remains uncertain. GLP-1 medications have demonstrated significant benefits in weight management, but how each individual reacts can vary. Open communication with healthcare providers is important for addressing concerns and ensuring proper care for anyone using these medications.
PatientsLikeMe is home to thousands of members seeking support, advice, and health tracking. We have a strong network dedicated towards helping everyone live a full and health life! Creating an account is free - join today.