Estimated reading time: 3 minutes
Lupus, officially known as systemic lupus erythematosus (SLE), is a chronic autoimmune disease where the immune system mistakenly attacks healthy tissues and organs. This can lead to inflammation and damage in various parts of the body, such as the skin, joints, kidneys, heart, lungs, brain, and blood cells.
Is Lupus More Common in Women or Men?
Lupus predominantly affects women, with approximately 90% of cases occurring in females. However, it does occur in men as well, albeit less frequently. The reasons for this gender disparity are not entirely clear, but hormonal and genetic factors are believed to play a role.
Common Symptoms for Women
Women with Lupus often experience symptoms such as:
- Fatigue
- Joint pain and swelling
- Skin rashes (butterfly-shaped facial rash)
- Photosensitivity
- Hair loss
- Issues related to organs like the kidneys and heart.
Women may also face more challenges during pregnancy, as the disease can affect fertility and increase the risk of complications.
Common Symptoms for Men
Lupus symptoms in men can differ, with some studies suggesting that men may be more prone to severe kidney involvement. Men with the condition may experience the following symptoms:
- Muscle pain
- Joint swelling
- Skin rashes
- And, like women, they can also face kidney and cardiovascular complications.
However, the overall prevalence of certain symptoms may vary between the genders.
Are There Any Hormonal Influences on Symptoms?
Hormonal factors, particularly estrogen, seem to contribute to the higher incidence of Lupus in women. The disease often emerges or flares during periods of hormonal fluctuations, such as puberty, pregnancy, and menopause. Men, on the other hand, might experience milder symptoms due to the lower levels of estrogen.
Are There Any Genetic Factors?
There is evidence to suggest a genetic predisposition to Lupus. In fact, certain genes associated with the disease are more common in women. However, the interplay of genetics, hormones, and environmental factors in the development and progression of the condition is complex and not yet fully understood.
How is Lupus Diagnosed and Treated?
Diagnosis often involves a combination of clinical symptoms, blood tests, and sometimes imaging studies. Treatment typically focuses on managing symptoms and preventing flare-ups. Medications like anti-inflammatory drugs, immunosuppressants, and corticosteroids are commonly prescribed. In severe cases, biologics and other advanced therapies may be used.
Interested in learning more? Over 38,000 people are managing their Lupus symptoms on PatientsLikeMe. Creating an account is free! Join today.