Inflammation is a hot topic. What's it all about? And what's the scoop on certain diets, foods and supplements, such as turmeric, when it comes to fighting inflammation?
What is inflammation?
Not all inflammation is "bad." Acute inflammation is part of the body's natural way of defending itself from foreign substances like viruses, bacteria, cuts and splinters. It may cause redness, swelling, heat and/or pain. The upside is, these symptoms are a sign that the body is responding after an injury or infection by triggering white blood cells and disease-fighting chemicals.
But some "other" kinds of inflammation — like chronic inflammation (which may include constant low-grade or systemic inflammation) and inflammation from autoimmune disorders (where the body attacks its own healthy cells as if they're foreign) — doesn't always show visible or obvious symptoms and can play a more long-term and complex role, according to Mayo Clinic.
Which diseases or conditions does it affect?
Mounting research shows that inflammation is a common underlying factor (and possibly a cause) in many — perhaps even all — diseases.
You've probably heard about the role of inflammation in arthritis or heart health. But researchers and doctors have also studied inflammation's link to a wide range of other diseases and conditions, including cancer, diabetes, Alzheimer's disease, multiple sclerosis (MS), Parkinson's disease (PD), major depressive disorder (MDD), post-traumatic stress disorder (PTSD) and ALS (note: in the case of ALS and some other conditions, researchers are still determining whether some inflammation may be protective rather than harmful, so more research is needed).
Over the past decade, scientists have also started to identify certain genes associated with inflammation, and research on that front continues.
What can food do?
Some people follow an "anti-inflammatory diet," but the science behind these particular diets does not clearly support the theory that they thwart inflammation, and doctors advise being wary of the health claims they make.
That said, taking steps to maintain a healthy weight and eat a variety of foods with anti-inflammatory properties (rather than follow a certain "Diet" with a capital "D") may benefit your health.
"Many experimental studies have shown that components of foods or beverages may have anti-inflammatory effects," says Dr. Frank Hu, professor of nutrition and epidemiology at the Harvard School of Public Health.
The team at Harvard says these foods have anti-inflammatory properties:
What's the deal with turmeric?
There's currently a lot of buzz around turmeric and some other supplements believed to help fight inflammation. Turmeric, a plant related to ginger, is a common spice known for its gold color and use in curry powder.
On top of being used as spice, it can be taken as a supplement. The main anti-inflammatory ingredient in turmeric is curcumin, which is available as a supplement on its own (the content of curcumin in turmeric spice is only around 3%, so curcumin supplements may pack more of an anti-inflammatory punch). One study found that curcumin may have the same anti-inflammatory effects as NSAID pain relievers, such as aspirin, ibuprofin, (Advil/Motrin) and naproxen (Aleve).
Preliminary studies have shown promise for curcumin's use in people with ulcerative colitis, multiple myeloma, lupus and depression. However, there's still a lack of conclusive research on the effects of turmeric or curcumin in people with many other conditions, so these supplements typically aren't recommended as part of a treatment plan at this point. Additional studies on curcumin are currently underway for people with some forms of cancer and neurodegenerative diseases, such as ALS, MS and PD.
Talk with your healthcare provider before starting any new vitamin, supplement or treatment.
What about other supplements?
Overall, the potential role of dietary supplements is "largely uncharted when it comes to carefully done clinical trials for safety and effectiveness," according to Brent Bauer, M.D., of the Mayo Clinic. Dietary supplements are not regulated by the U.S. Food and Drug Administration (FDA) for safety and effectiveness. Keeping that in mind, here are some other supplements with possible anti-inflammatory effects that researchers have studied to some extent, the Mayo Clinic says:
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- Tomatoes
- Olive oil
- Green leafy vegetables, such as spinach, kale and collards
- Nuts like almonds and walnuts
- Fatty fish like salmon, mackerel, tuna and sardines
- Fruits such as strawberries, blueberries, cherries and oranges
- Refined carbohydrates, such as white bread and pastries
- French fries and other fried foods
- Soda and other sugar-sweetened beverages
- Red meat (burgers, steaks) and processed meat (hot dogs, sausage)
- Margarine, shortening and lard

- Cat's claw (Uncaria tomentosa) — This could ease rheumatoid arthritis joint pain and osteoarthritis knee pain during activity, but more research is needed.
- Devil's claw (Harpagophytum procumbens) — It's commonly used in Europe and may be effective in the short-term treatment of osteoarthritic pain.
- Mangosteen (Garcinia mangostana) — Made from the mangosteen fruit, this supplement may have anti-allergy, antibacterial, antifungal, antihistamine and anti-inflammatory qualities, but more research in humans is needed.
- Milk thistle (Silybum marianum) — This may help improve organ function in people with cirrhosis, a chronic liver disease. It may also be helpful in treating chronic hepatitis. But more research is needed before it can be recommended.
