What is methylenetetrahydrofolate reductase deficiency?
Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that is encoded by the MTHFR gene. Mutations in this gene are associated with MTHFR deficiency which may result in intellectual disability, psychosis, weakness, ataxia, spasticity and homocystinuria due to elevated blood levels of homocysteine.
How do members experience methylenetetrahydrofolate reductase deficiency?
Top 5 symptoms reported by people with methylenetetrahydrofolate reductase deficiency*
*Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
Top treatments taken by people for methylenetetrahydrofolate reductase deficiency*
We currently don't have enough shared data that is made public for this condition.
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Who has methylenetetrahydrofolate reductase deficiency on PatientsLikeMe?
Age
| Age | Proportion | # of patients |
|---|---|---|
| <20 | 3 | |
| 20s | 14 | |
| 30s | 69 | |
| 40s | 91 | |
| 50s | 120 | |
| 60s | 78 | |
| 70+ | 37 |
Distribution of sex
Sex
| Sex | Proportion | # of patients |
|---|---|---|
| Male | 54 | |
| Female | 354 |
Talk to people with methylenetetrahydrofolate reductase deficiency
435
435
members say they have this condition